I was at an AD today and tried on the 42 and 45 PO. For the 45, he lug were fully on top of my wrist, but almost went totally from one one of my wrist to the other. Next to the 45, the PO looked a lot smaller, but 42 is a very nice sized watch, I think I just lost some perspective comparing it to such a large watch. So when do you think a watch is too big- if lug to lug the watch is wider than your wrist?
On a side note I decided to have a little fun there and try on a Panerai (not sure which one), Breitling Seawolf and Super Avenger, and a Rolex Sub. I love watch shopping!